MyBioSource.com's Anti-Serotonin transporter antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The Anti-Serotonin transporter antibody was generated using 5-HTTLPR, 5HTT, hSERT, SERT, SERT1, and SLC6A4 as the antigen and it reacts with Human.
Description
Description: Rabbit IgG polyclonal antibody for Sodium-dependent serotonin transporter(SLC6A4) detection. Tested with WB in Human.
Background: SLC6A4(Solute carrier family 6, member 4), also known as SERT(serotonin transporter), is a monoamine transporter protein. The SLC6A4 gene spans 31 kb and contains 14 exons. This protein integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. This transport of serotonin by the SERT protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is the target of many antidepressant medications, including those of the SSRI class. It is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, post-traumatic stress disorder and depression-susceptibility in people experiencing emotional trauma